Posted by undopaminergic on January 25, 2021, at 2:37:25
In reply to Re: parnate, posted by creepy on January 24, 2021, at 18:31:16
> I agree about the washout. But the doctors at this clinic are really ignorant of a lot of pharmacology, especially MAOI it took me a huge effort to even get emsam prescribed.
>
> Selegiline has stimulant qualities too for a short while then after that its kind of sleepy actually.
> Does parnate remain stimulating? Im guessing the sedation is a quality of all MAOI via melatonin.
>Phenelzine has a GABAergic metabolite, largely responsible for its calming and sedative effects; this is unlike tranylcypromine and selegiline. Selegiline has (l-) amphetamine metabolites, and tolerance easily develops, as happened to me. I would expect tranylcypromine too to produce tolerance.
-undopaminergic
poster:undopaminergic
thread:1113460
URL: http://www.dr-bob.org/babble/20210120/msgs/1113515.html