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To SLS - clorgyline and imidazoline

Posted by linkadge on January 2, 2020, at 15:52:40

Hi SLS,

I recall you once saying that you had a good response to the drug clorgyline. I was reading about it on Wikipedia and apparently (in addition to being a potent MAOI) it is an even more potent agonist at the imidazoline receptors (in the PICOMOLAR concentration):

https://en.wikipedia.org/wiki/Clorgiline

Imidazoline receptors have been studied in depression and may have some antidepressant effect. I believe agmatine (a cheap supplement with purported antidepressant effect) is also an imidazoline agonist.

I wondered if you considered adding agmatine to your current regiment? (with or without a MAOI).

Anyhow, just an interesting finding.

Linkadge



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