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Re: Anybody had luck with protriptyline (Vivactil)?

Posted by JohnL on April 14, 2000, at 3:16:19

In reply to Anybody had luck with protriptyline (Vivactil)?, posted by Stephan on April 13, 2000, at 23:12:59

> This drug is quite similar to reboxetine in that it hits norepinephrine very hard. I'm surprised more people haven't tried it. I hope to try it in the not-so-distant future, since I had my longest responses with desipramine and nortriptyline.

My pharmacist says only one person in our town is on Vivactil. I think it is a neglected underused antidepressant. Desipramine or Nortriptyline probably have slightly milder anticholinergic side effects though.

I saw a comment from one doctor that said Vivactil would be a whole lot more popular if Prozac hadn't been invented. It is more activating than the other TCAs. The SSRIs kind of pushed a lot of yesterday's effective antidepressants into the closet. And I've seen monograph comments indicating Vivactil is "suitable for the apathetic withdrawn depressed patient".

I tried Vivactil briefly for about a week. The only reason I stopped was because it increased my tinnitus to an intolerable level.


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