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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by blueberry on November 17, 2006, at 18:19:35
I am hoping to collect a wide variety of information and opinions on St Johns Wort. Any and all information is great.
I know the basics of it...serotonin, norepinephrine, dopamine, gaba, and glutamate reuptake inhibitor. I think the MAOI activity of it is only found in the raw herb but not extracts? My only experience is with the brand Kira LI160. I wonder about other brands.
Anyway, your opinions and info greatly appreciated!
Posted by aeon on November 17, 2006, at 18:49:45
In reply to Aeon and all...Your Opinions on SJW?, posted by blueberry on November 17, 2006, at 18:19:35
Hi Blueberry
SJW is a good herb, it is partly anti-inflammatory. Contains small amounts of Quercetin. I have tried it many times in all different ways, but it never really touches my depression all that much, only a slight improvement, even though I desperately wanted it to.
I would say don't bother., it is too weak for serious profound depression.
Posted by nolvas on November 17, 2006, at 19:08:40
In reply to Re: Aeon and all...Your Opinions on SJW?, posted by aeon on November 17, 2006, at 18:49:45
You probably know this site but I'll post in just in case. Has a lot of useful info about sjw, hence the name :)
Posted by linkadge on November 17, 2006, at 19:31:30
In reply to Re: Aeon and all...Your Opinions on SJW?, posted by nolvas on November 17, 2006, at 19:08:40
I wouldn't say don't bother. It has been played in the media as being innefective for anything but mild to moderate depression, however there are studies showing that it is effective in severe depression. It is advertised as only being effective for mild-moderate depression as this is what keeps the "system" in check.
Head to head trials with stronger drugs like paxil have found equivilant results. In a few animal studies, SJW has been more effective than SSRI's. SSRI's often fail in the forced swim test in mice.
Of course it depends on your depression. There will always be people who don't respond to any given drug.
The case for SJW has been rife with controversy and scandal. A few studies procalimed that SJW was no better than placebo, while failing to mention that the comparior drug, always SSRI's also failed in such studies.
I personally know of a few people who failed to respond to SSRI's but responded to SJW.
But, in the end, let the efectivness of the drug quantize itself. Don't let you opinion of how a treatment should work influence how it does work.
Linkadge
This is the end of the thread.
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