Psycho-Babble Alternative Thread 427706

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SSRI/dopamine antagonism

Posted by raybakes on December 11, 2004, at 9:13:12

Just came across this study that found that SSRIs upregulate the dopamine transporter (DAT).

"The results demonstrated the inhibition of SERT by SSRI in human in vivo during the chronic treatment and, unexpectedly, an elevation of DAT. This apparent SSRI-induced modulation of the dopamine system may be associated with the side effects of these agents, including sexual dysfunction."


http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12589396&dopt=Abstract

Ray

 

Redirect: SSRI/dopamine antagonism

Posted by Dr. Bob on December 13, 2004, at 3:09:36

In reply to SSRI/dopamine antagonism, posted by raybakes on December 11, 2004, at 9:13:12

> Just came across this study that found that SSRIs upregulate the dopamine transporter (DAT)...

Sorry to interrupt, but I'd like to redirect this thread to the main Psycho-Babble board. Here's a link:

http://www.dr-bob.org/babble/20041211/msgs/428740.html

Thanks,

Bob


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