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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by ed nieg on March 16, 2019, at 18:58:18
I am trying to decide which stimulant would be safer and more effective to augment Parnate in the case of TRD. I have never completely remitted despite countless combinations of psychiatric/recreational drugs and ECT. Stimulants are one of the only meds I haven't tried. I would be using a very low dosage to start out with; I'm trying to take the most prudent approach possible. I'm wondering if anyone more informed about stimulants than me can state which has the superior pharmacology for depression/anhedonia.
Posted by Christ_empowered on March 16, 2019, at 20:16:35
In reply to Methylphenidate or d-amphetamine to augment TCP?, posted by ed nieg on March 16, 2019, at 18:58:18
hi. parnate+amphetamine was once, many moons ago, an acceptable treatment for some forms of depression. i think usually the dose is kept low, but the late Dr.Ivan Goldberg (his website may or may not still be up and running...) reported maxing out at 60mgs/dexedrine with the maoi, and other shrinks sometimes used Desoxyn (rx methamphetamine), so...
it seems that there's some room for dosage adjustment.
Posted by rjlockhart37 on March 19, 2019, at 15:53:19
In reply to Methylphenidate or d-amphetamine to augment TCP?, posted by ed nieg on March 16, 2019, at 18:58:18
my guess would be methyphendiate, because it has weaker actions than dexamphetamine. Dex is more phsyically stimulating, like increased heart rate and energy levels. methypheidate is less, but still....basially ritilin is just a dopamine reptake inhibtor, d-amp releases dopamine into the synapse, that's why it's a bit more stimulating. But....if it was low dose like 10mg, it could provide benefit. Higher doses is why d-amp is sometimes risky with parnate because of significant dopamine increase and heart rate, and also alot of other reasons too
This is the end of the thread.
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