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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by missliz on April 18, 2007, at 1:59:16
Parnate is only available as a generic now. Since it was basicly manufactured as a generic for the last eight years or more- this may not be anything to worry about, but it's now made by a generics company as of last summer.
Anybody taken it? Any problems? Some generics are acceptable, some aren't worth the blackboard chalk they're made of.
Parnate is a great drug- if you can find a doctor who'll bother to read the instructions. Dopaminergic and shoos away the social phobia. But the pills have to actually work..
Posted by willyee on April 19, 2007, at 23:10:24
In reply to Generic trancylpropamine (Parnate), posted by missliz on April 18, 2007, at 1:59:16
> Parnate is only available as a generic now. <
Yess it is now available as a generic,HOWEVER as far as i know,and me and my pharmsisct checked on this the other day that brand parnate is still readly available.
Generics are sometimes automaticaly given,speak to ur pharmacy and make sure they are getting u brand are youll likly recieve generic.
If im wrong here ill be calling glaxco asap.
Posted by Jedi on April 20, 2007, at 3:14:35
In reply to Generic trancylpropamine (Parnate), posted by missliz on April 18, 2007, at 1:59:16
So far so good on generic tranylcypromine. I switched from Nardil about six weeks ago, because of a weight issue with Nardil. I've titrated up to 80mg with no side effects other than some afternoon somnolence. This seems to be improving. For me Parnate does not cause the severe sweet carbohydrate cravings like Nardil did. No return of the major depression, I'm crossing my fingers because I really want to stay on this med. I augment with 1-2mg of clonazepam for my social anxiety. At night I use Benadryl and Seroquel for the med induced insomnia.
Take care,
Jedi
Posted by missliz on April 20, 2007, at 14:34:01
In reply to Re: Generic tranylcypromine (Parnate), posted by Jedi on April 20, 2007, at 3:14:35
Why are you on a dirty brain burning novel like Seroquel at six weeks?
That's a big dose of trancyl*** and you should be out having a powerwalk every day, not needing a nap. I know about the sleep problems, and I know about the AP to keep you sort of sane through the switch, but at six weeks you should be coming off of it. One of the great beauties of the MAOI is that in psychotic depression, the psychosis goes away when the depression goes away. And the depression goes away. But you won't know it, dear, if you're that drugged up.
These drugs always work, unless the doctor can mess them up to keep his billable hours up and the drug reps happy. You need to talk to an advocate if you get ignored.
If you need a nap you're overmedicated as H. Just the benedryl hangover will keep you in la la land. You need to talk to your doc.
I've used these drugs for years, and the biggest problems with them are manufacturers who want to get rid of them and doctors with no proper training in how to use them. They're a rough ride on but at six weeks...
I do not like to comment other peoples doctors judgement, but you need to go ask questions. Trancylpro** will cause remission, it's the only drug that can, but with grotty novel APs in there it may not have a chance.
Besides- Parnate is dopaminergic. Bad mix with an AP if you actually want to feel good. If you need something- everybody else takes mood stabilizers. I like Trileptal, personally.
Go read Ken Gillman on MAOIs at <www.psychotropical.com> Amazingly good doctor. Actually knows what he's talking about.
Posted by Jedi on April 20, 2007, at 15:18:28
In reply to Re: Generic tranylcypromine (Parnate), posted by missliz on April 20, 2007, at 14:34:01
Hi Missliz,
Thank you for the advice. I'll try without the Seroquel. I've never been psychotic, just taking 25 to 50mg for insomnia. I'd only been getting about four or five hours sleep per night and that wasn't making it. Thank you for the reference. I'm in a small town with next to no choices for PDOCS, absolutely no good ones. The last time I traveled to a major city to see supposedly one of the best PDOCS in the country; he took me off Nardil and put me on Prozac. Now this was for treatment resistant atypical depression, with already multiple failed trials on SSRIs, including Prozac. Then I find out he has a piece of the company. Great, please just mess with my brain.
Take care,
Jedi
Posted by missliz on April 20, 2007, at 18:11:05
In reply to Re: Generic tranylcypromine (Parnate) » missliz, posted by Jedi on April 20, 2007, at 15:18:28
Hey, I've been through all of it- and I know about the sleep. Going on Parnate can really be riding the dragon, and MAOIs take eight weeks. Too much can mess with your heart rythym, but the right amount is a true blessing. Desyryl does sleep and can be a good choice. I used a lot of that benzo based sleeping pill for several months. Give up anything with caffeine for a while, and you can always crank down the dose a bit. Or a lot.
I have my own evil stories with Seroquel, and I don't promote doing things without medical supervision, but you have a right to treatment as it's in your best interests. Get educated- and taper that Seroquel. You may find a few cognitive shockers, because Seroquel is mental herbicide while an MAOI is Miracle Gro. Do not ever just stop something cold turkey; your brain works hard and needs to adjust to things, it's touchy like that.
Go read Dr Gillmans site. I know Ken personally, and he's a great guy, on the patients side. You need to know what he has to say, he would give Parnate to his family. And psychiatrists are so influenced by drug companies, you need to educate yourself.
I have hundreds of files of stuff on this- but Psychotropical is a good starting place.
MAOIs will pick you up by the scruff of the neck and just shake that brain wiring into a new matrix. It's hard- and it's hard to know what to do with yourself being a lot better. But life can be so amazingly wonderful, and MAOI is nothing compared to what people with other illnesses put up with.
I'd just stay away from novel anti depressants. They have weird interactions with a lot of drugs and the headshrinkers are too lazy to read the instructions. Make you so fat your knees will blow out.
Good luck and safe journey. Hope it's wonderful in the Emerald City.
Posted by halcyondaze on April 22, 2007, at 20:41:59
In reply to Re: Generic tranylcypromine (Parnate), posted by Jedi on April 20, 2007, at 3:14:35
I'm on 120 mg Parnate.
It's all brand name. Slightly more money but worth it, since this drug is so fickle I don't want to mess with whatever is working for me.
Posted by missliz on April 22, 2007, at 21:31:34
In reply to Re: Generic tranylcypromine (Parnate), posted by halcyondaze on April 22, 2007, at 20:41:59
No Sweet Pea, real Parnate as properly made hasn't been available for over ten years. It was genericized by virtue of reformulation a while back; Now it's only available as a legal generic made by PAR labs, who make pretty decent stuff as generics go. But still...
I am in the USA, like the board, so if you're writing in from somewhere else, well, whatever. If You're getting brand name in this country it's leftovers. The thing changed in, July? last year?
Glad you're doing well, but for me, restarting it again finally I want the word, from other FDA victims. Given Phizers' behavior and the Nardil disaster I should ask around.
Since the money is in medicating peoples boredom and unhappiness with SSRIs the really sick people have been screwed over by Big Pharma trying to completely jettison MAOIs. What ever you're taking has a certain bioavailability and I bet it's different from the glowing scarlet carnuba wax of the original thing.
Posted by halcyondaze on April 23, 2007, at 7:27:39
In reply to Re: Generic tranylcypromine (Parnate), posted by missliz on April 22, 2007, at 21:31:34
I contacted GSK on this matter.
The formulation used to contain sugar (the black Parnate writing) but now contains canuba wax (the red imprinted Parnate without black writing). I am frequently given entire bottles since I take so much and all have said GSK on them.
Parnate went generic one year ago. It is still availble as brand, according to Glaxo Smith Klein, my pharmacist, and my psychopharmacologist.
Posted by chante on April 25, 2007, at 0:29:29
In reply to Re: Generic tranylcypromine (Parnate), posted by missliz on April 20, 2007, at 14:34:01
Do you think it's ok to take parnate with zoloft.. zoloft keep make me sleep so much but help for my stresss and depre.. just need get my stuff done I can't function always on the coach all day but happy>>>>>
Posted by missliz on April 25, 2007, at 0:43:32
In reply to Re: Generic tranylcypromine (Parnate), posted by chante on April 25, 2007, at 0:29:29
NO!
NO NO NO NO NO!
Read the intructions. If you mix an SSRI with an MAOI your brain will cook in seratonin syndrome or Neuroleptic malignant syndrome. Makes people vegetables.
SSRIs bite. I know they get mixed- but it's kind of like mixing a Red Hot with a LemonHead. Oookey- but all sugar.
If you want The Stuff, you'll have to find a doctor who'll do them- or put your foot down with yours. Then wash out two to four weeks dependent on the half life of the junk that doesn't work now because you can seize if they mix in your brain.
It's totally worth it- but these are the real drugs that work, not the nut on Lilly's fleet of Gulfstreams. They don't mix.
You feel like crap because your on a drug designed to make stockholders happy, not you. You need to get on your Psydoc about it. Or get an advocate on the doc, and find out if he has stock options in the company.
This is the end of the thread.
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