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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by mrsmith on March 15, 2007, at 12:39:33
I've posted on other boards that long-term dexedrine use has made me "alert but anhedonic". Maybe dysregulated dopamine system is the culprit. Abilify is marketed as a dopamine regulator. Any thoughts on whether adding abilify can make me not only alert but ALIVE?
Posted by TheMeanReds on March 15, 2007, at 13:17:56
In reply to Ablify + Stimulant-Induced Dopamine Tone, posted by mrsmith on March 15, 2007, at 12:39:33
Abilify I think gives me energy, because I cannot take it at night. Seems to be a good anti depressant for me. I dont know if its a 'miracle' drug, but it makes me feel like I took a bong hit. Except no paranoia or cottonmouth. Been on it for a couple weeks, I think. It definately made me more interested in things. Like this board. I take it in the morning, and then I check my mail and that stuff. Sometimes I cant get off this board. Gotta drag myself from the puter.
Good Luck
> I've posted on other boards that long-term dexedrine use has made me "alert but anhedonic". Maybe dysregulated dopamine system is the culprit. Abilify is marketed as a dopamine regulator. Any thoughts on whether adding abilify can make me not only alert but ALIVE?
Posted by mrsmith on March 15, 2007, at 14:06:26
In reply to Re: Ablify + Stimulant-Induced Dopamine Tone » mrsmith, posted by TheMeanReds on March 15, 2007, at 13:17:56
Glad to hear abilify helps, altho that bong hit is probably cheaper!
> Abilify I think gives me energy, because I cannot take it at night. Seems to be a good anti depressant for me. I dont know if its a 'miracle' drug, but it makes me feel like I took a bong hit. Except no paranoia or cottonmouth. Been on it for a couple weeks, I think. It definately made me more interested in things. Like this board. I take it in the morning, and then I check my mail and that stuff. Sometimes I cant get off this board. Gotta drag myself from the puter.
>
> Good Luck
>
>
> > I've posted on other boards that long-term dexedrine use has made me "alert but anhedonic". Maybe dysregulated dopamine system is the culprit. Abilify is marketed as a dopamine regulator. Any thoughts on whether adding abilify can make me not only alert but ALIVE?
>
>
Posted by Phillipa on March 15, 2007, at 21:04:00
In reply to Re: Ablify + Stimulant-Induced Dopamine Tone, posted by mrsmith on March 15, 2007, at 14:06:26
You find ambilify is an antidepressant? Aren't they saying that about seroquesl too? Love Phillipa ps this board is addicting and there is an addiction button somewhere. Haven't used it some suggest I should.
Posted by med_empowered on March 15, 2007, at 21:18:36
In reply to Ablify + Stimulant-Induced Dopamine Tone, posted by mrsmith on March 15, 2007, at 12:39:33
Abilify, for me, is kind of an odd drug. On lower doses, I felt calmer and more focused, and it smoothed over paranoia w/o totally eliminating it (I took it for bipolar "issues"); on higher doses, it was basically just a neuroleptic, albeit one that was quite tolerable.
Intuitively, it seems to me that a low (below 10mgs) dose of abilify would smooth out a stimulant, relieving tension and maybe doing some sort of anti-depressant, anti-anxiety work. If you have problems with mood changes in between dex doses, it might help that, too, b/c of the partial D2 agonism and b/c of the serotonin action. Abilify does tend to cause akathisia in what seems like a lot of people, at least w/ the higher (10mgs+) dosages; if you start @ 2-5 (both 2 and 5mgs tabs are now available, btw), that might be less of a problem.
If you've tried other things already, this sort of combo might be worth a try. Since neuroleptics tend to act pretty quickly, I would think you'd only need a brief trial to see whether or not this particular combo is going to benefit you.Good luck.
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