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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by jealibeanz on February 19, 2007, at 21:25:27
When one takes an SSRI, SNRI, MAOI, TCA, or Buspar, what are the possible physiological effects on the brain and the rest of the body?
I am asking in reference mainly to weight gain. I know that some believe SSRI's can make people less sensitive to insulin (or even the opposite can occur). I'm not sure why the others cause weight gain.
There are theories about temporary thyroid dysfunction. I can't think of any others.
Does anyone know of any theories that specialists are fairly certain of?
Posted by linkadge on February 20, 2007, at 7:25:04
In reply to Serotonin and Physiology, posted by jealibeanz on February 19, 2007, at 21:25:27
This is one of the main reasons I believe that the serotonin reuptake system is not implicated in depression.
When you take an SSRI, you affect the serotonin reuptake mechanism throughout the whole body.
All sorts of strange things can occur, from affect on bones, to the heart, stomach, etc.
Linkadge
Posted by jealibeanz on February 20, 2007, at 10:59:29
In reply to Re: Serotonin and Physiology, posted by linkadge on February 20, 2007, at 7:25:04
> This is one of the main reasons I believe that the serotonin reuptake system is not implicated in depression.
>
> When you take an SSRI, you affect the serotonin reuptake mechanism throughout the whole body.
>
> All sorts of strange things can occur, from affect on bones, to the heart, stomach, etc.
>
> Linkadge
>
>
>I'm not quite sure what you mean by "the serotonin reuptake system is not implicated in depression." Do you mean the current drugs are a poor method of treatment, or that it is not proper to target serotonin?
Posted by linkadge on February 20, 2007, at 13:45:35
In reply to Re: Serotonin and Physiology, posted by jealibeanz on February 20, 2007, at 10:59:29
>Do you mean the current drugs are a poor method >of treatment, or that it is not proper to target >serotonin?
Sorry, I should have been more specific. Hundreds of studies attempting to link depression to an abnormality in the serotonin transporter have been inconclusive.
If serotonin is abnormal in depression, it is likely that it is due to some abnormalitiy other than abnormal seronin reuptake.
Linkadge
This is the end of the thread.
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