Psycho-Babble Medication Thread 678892

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Can meds have a more positive response at lower d?

Posted by chiron on August 21, 2006, at 22:35:24

I'm currently on Cymbalta, which originally on 30 mgs I found helpful for my anxiety & depression. I was still feeling blah, so we raised it eventually to 120 mgs. It seemed that about the same time I became more irritable and depressed. When I told my pdoc this he thought it was odd, because usually levels are raised to get a more positive response rather than lowered.
Other experiences?

 

Re: Can meds have a more positive response at lower d? » chiron

Posted by Maxime on August 22, 2006, at 14:02:20

In reply to Can meds have a more positive response at lower d?, posted by chiron on August 21, 2006, at 22:35:24

My psychiatrist explained med increases to me this way: "you keep increasing the dosage until you experience side you can't tolerate. It's like filling a bathtub and making sure it doesn't overflow". It's a simplistic explanation and that's why I like it. Maybe you just needed to stay at 30 mg for a longer period. Now you need to decrease the med slowly, until you no longer feel the irritability BUT still feel the positive effects of the med.

Is there any other reason why you have become irritable? Are you sure it's the med?

Maxime


> I'm currently on Cymbalta, which originally on 30 mgs I found helpful for my anxiety & depression. I was still feeling blah, so we raised it eventually to 120 mgs. It seemed that about the same time I became more irritable and depressed. When I told my pdoc this he thought it was odd, because usually levels are raised to get a more positive response rather than lowered.
> Other experiences?

 

Re: Can meds have a more positive response at lower d? » chiron

Posted by Phillipa on August 22, 2006, at 19:34:00

In reply to Can meds have a more positive response at lower d?, posted by chiron on August 21, 2006, at 22:35:24

If it was helpful why did he raise the dose from 30mg? And the manufacturer says above 60mg no improvement unless that's been changed. Love Phillipa

 

Re: Can meds have a more positive response at lower d?

Posted by qbsbrown on August 26, 2006, at 16:19:54

In reply to Can meds have a more positive response at lower d?, posted by chiron on August 21, 2006, at 22:35:24

Chiron, i would say most definantly that too high of a dose can have bade effects. Some believe that it will only raise the side effects, but from personal experience, i experience different.

I'm a low dose responder. My doc kept/keeps pushing me to go up, first on paxil, then celexa/lexapro. I found as i went lower and lower, my beneficial effects got better and better.

In my opinion, yes, too high of a dose can have adverse effects, not just more side effects.

Brian


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