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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by theo on May 24, 2005, at 15:19:27
Scott,
I remember a while back you were taking imipramine and now you are taking nortriptyline. How would you compare/differentiate the two?
Posted by SLS on May 24, 2005, at 19:24:51
In reply to Question for SLS-imipramine vs nortriptyline, posted by theo on May 24, 2005, at 15:19:27
> Scott,
>
> I remember a while back you were taking imipramine and now you are taking nortriptyline. How would you compare/differentiate the two?Both drugs are potent antidepressants and have great track records for getting people well. As one might expect, there are those whom will respond to one but not the other. If I knew in advance that I would respond to both drugs, I would choose nortriptyline. Its anticholinergic side effects are substantially milder and less assaulting on cognition. Imipramine probably has the potential to get more people well than nortriptyline, but not by so much that I would make it my first choice. I would choose nortriptyline. Just be aware that monitoring blood levels or nortriptyline can be very important. A therapeutic window exists for this drug. A range has been established that lies between 50-150 ng/ml. There is, of course, a minimum dosage at which a person will respond. However, it is actually possible to lose the antidepressant response by going too high with the a dosage. For me, I lose the benefit of nortriptyline if I take more or less than 100mg.
- Scott
Posted by theo on May 24, 2005, at 23:04:15
In reply to Re: Question for SLS-imipramine vs nortriptyline, posted by SLS on May 24, 2005, at 19:24:51
This is the end of the thread.
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