Shown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by jessers11581 on April 20, 2005, at 19:56:08
Does Cymbalta only affect serotonin and norepinephrine, or does it increase dopamine as well? If so, maybe I don't need to add Wellbutrin...
Posted by Phillipa on April 20, 2005, at 20:45:34
In reply to another Cymbalta question, posted by jessers11581 on April 20, 2005, at 19:56:08
I don't think it touches dopamine, but I'm not one of the med experts. Fondly, Phillipa
Posted by Colleen D. on April 21, 2005, at 7:28:33
In reply to another Cymbalta question, posted by jessers11581 on April 20, 2005, at 19:56:08
Here's a link to a neat chart that lists what the different meds affect.
http://sl.schofield3.home.att.net/medicine/psychiatric_drugs_chart.html
:-) Colleen
Posted by alienatari on April 21, 2005, at 9:07:09
In reply to It doesn't affect dopamine... » jessers11581, posted by Colleen D. on April 21, 2005, at 7:28:33
thats a great chart. thanks for the link :)
> Here's a link to a neat chart that lists what the different meds affect.
>
> http://sl.schofield3.home.att.net/medicine/psychiatric_drugs_chart.html
>
> :-) Colleen
Posted by cache-monkey on April 21, 2005, at 12:03:00
In reply to another Cymbalta question, posted by jessers11581 on April 20, 2005, at 19:56:08
According to a couple of studies done on rats, Cymbalta (duloxetine) showed increases in dopamine but these were much weaker than the effect on norepinephrine and somewhat weaker than its effects on serotonin.
[ http://www.biopsychiatry.com/alp2ant.htm
and http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9048781&dopt=Abstract ]I'd think that at its therapeutic dose the norepinephrine increase would be dominant, the serotonin increase secondary, and the dopamine increase negligible.
HTH,
cache-monkey> Does Cymbalta only affect serotonin and norepinephrine, or does it increase dopamine as well? If so, maybe I don't need to add Wellbutrin...
This is the end of the thread.
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