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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by Sarah T. on February 23, 2005, at 23:04:13
Sometime in the past year, I remember hearing that Serzone might cause liver damage. I thought that it was going to be withdrawn from the market, and I think it actually was withdrawn overseas and possibly in Canada. Is it still available in the U.S.? Does anyone here take it? If so, have you also taken Trazadone? How does Serzone compare with Trazadone? Does anyone know what it was about Serzone that caused the liver problems?
Posted by SadDoggie on February 24, 2005, at 0:19:57
In reply to Is Serzone still available in the U.S.?, posted by Sarah T. on February 23, 2005, at 23:04:13
Sarah,
Serzone was withdrawn overseas but the company withdrew it themselves here in the US because of the liver injury in some people. Sales plummeted so I guess they figured to just withdraw it. You can try trazadone which might be similar. As a guy I wouldn't try it because it can cause priapism in some men (erection that doesn't go away), and this can be very dangerous. But a woman would not get this obviously, so it's safe for you.
SadDoggie> Sometime in the past year, I remember hearing that Serzone might cause liver damage. I thought that it was going to be withdrawn from the market, and I think it actually was withdrawn overseas and possibly in Canada. Is it still available in the U.S.? Does anyone here take it? If so, have you also taken Trazadone? How does Serzone compare with Trazadone? Does anyone know what it was about Serzone that caused the liver problems?
Posted by Sarah T. on February 24, 2005, at 0:36:49
In reply to Re: Is Serzone still available in the U.S.?, posted by SadDoggie on February 24, 2005, at 0:19:57
Hi Sad Doggie. Thanks for the information.
Posted by Sarah T. on February 24, 2005, at 0:48:17
In reply to Re: Is Serzone still available in the U.S.?, posted by SadDoggie on February 24, 2005, at 0:19:57
I wonder how former Serzone users are managing to do without it, especially if they found it helpful for their depression. Are they (or are the women) switching to Trazadone?
Posted by HappyGirl on February 24, 2005, at 0:55:47
In reply to Re: Is Serzone still available in the U.S.?, posted by SadDoggie on February 24, 2005, at 0:19:57
Hi:
Serzone was taken out from the market already, last year or so, however the generic form of Serzone, "Nefadozone'" is still available here, in USA.In the past, I took the Serzone for about three or four years in conjuction with the Wellbutrin sr, as for Anti-Depressant combo. This combo. did help my Bp depression.
Having started out on a small-dosage, from 150 mg. and went up to the around the 450 mg. which was 'mass' dosage. I took the Serzone as 'mono' A.D. therapy and added the WB sr due to the concentration problem brought on by the Serzone or my BP itself, which I can not remember. Anyway, in spite of the 'bad press' surrounding the Serzone, I NEVER had any problem as to 'Liver' although I was advised to take 'test' periodically, two to three times a year for taking the Serzone. It was one of 'Miracle' A.D.s, because I was some allergic reaction to all of SSRIs, then to be honest, the Serzone offered me a great relief and peace in mind. Plus, WB sr saved me 'concentration,' 'motivation' and others related by working together with the Serzone. This combo. gave me such a relief that I still giving profound credit/gratitude to my pdoc. who rx'ed this 'wonderful' combo. However, for some reason, Serzone's effectiveness started to 'fade away' along with a nasty S.E. which I needed to make a trip several times during my nightly sleep. Then, afterwards, my pdoc. rx'ed the Trazodone. I started out on a tiny dosage, 50 mg. and now, after 7-8 months' I've been taking the 150 - 225 mg. before bed.
As to Serzone and Trazodone, ... in my experience, ... Trazodone is, as you might know, is an older class of A.D., while Serzone is a newer A.D. For me, Trazodone is more 'potent' than Serzone along with its side-effect. At the beginning on the Trazodone, I was so drowsy lasted next day, then for awhile, I needed to quit. However, for a good A.D. efficacy of the Trazodone, I gave one more 'shot' to take it again. The second time around on the Traz., I did well and has been working good on my Bp depression, not perfect, but 'acceptable' range.
In my 'personal' opinion, the Trazodone is a kind 'raw' feelings at the beginning while the Serzone is 'refined' type of A.D., ... however, the efficacy of the Trazodone has more 'power' than its Serzone.
Both, Serzone and Trazodone has similar efficacy, naming, 'Three,' ... 'Anxiety,' 'Depression,' and 'some for even OCD' brought on by Bp depression.
H.G.
Posted by Optimist on February 24, 2005, at 11:23:35
In reply to Re: Is Serzone still available in the U.S.?, posted by HappyGirl on February 24, 2005, at 0:55:47
Serzone, Trazodone, and Remeron aren't supposed to be very robust AD's on their own but work better if augmented with other AD's. I wouldn't recommend monotherapy unless you have very mild depression/anxiety.
Posted by Phillipa on February 24, 2005, at 17:40:42
In reply to Re: Is Serzone still available in the U.S.?, posted by Optimist on February 24, 2005, at 11:23:35
What would you suggest taking remeron with. I'm on it to help with sleep. Fondly, Phillipa
Posted by Optimist on February 24, 2005, at 23:10:35
In reply to Re: Is Serzone still available in the U.S.? » Optimist, posted by Phillipa on February 24, 2005, at 17:40:42
> What would you suggest taking remeron with. I'm on it to help with sleep. Fondly, Phillipa
I think it really depends what your deficits are. I don't know your problems well enough to point you in the right direction. Some one else may be able to give you a more informed answer.
Brian
This is the end of the thread.
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