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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 15 of 15. This is the beginning of the thread.
Posted by linkadge on January 14, 2004, at 10:41:43
Has anyone here tried mirapex ??
With what other medications ?What did it do for you ??
Linkadge
Posted by crazychickuk on January 14, 2004, at 10:49:57
In reply to Anyone tried mirapex ?, posted by linkadge on January 14, 2004, at 10:41:43
Hello linkadge, my uncle (family freind) was prescribed that a few mnths back for parkinsons, it has helped with his shakes, he also takes valuim and effexor for his severe anxiety, he is doing pretty well, i will ask him more about it if you want to?
Donna
Posted by SLS on January 14, 2004, at 11:41:38
In reply to Anyone tried mirapex ?, posted by linkadge on January 14, 2004, at 10:41:43
> Has anyone here tried mirapex ??
Hi.
I know of a few people who have tried it and eventually gave up on it. They reported a significant antidepressant effect early on. Then, for some reason, they began to feel sedated and became somnolent. I have very little idea how prevalent that pattern of response is.
You might also take a look at ropinerole (Requip). My doctor mentioned it as a possible treatment for me.
- Scott
Posted by linkadge on January 14, 2004, at 12:17:12
In reply to Re: Anyone tried mirapex ?, posted by crazychickuk on January 14, 2004, at 10:49:57
If he happens to mention weather it effected his mood for the positive (or negative)
it is suppsed to have some significant antidepressant properties.
Linkadge
Posted by Ame Sans Vie on January 14, 2004, at 13:12:57
In reply to Re: Anyone tried mirapex ?, posted by linkadge on January 14, 2004, at 12:17:12
What SLS said is right on. Mirapex was a miracle for me when I first tried it, providing me with boundless motivation, creativity, and freedom from depression (I believe I was taking it along with Klonopin and Lexapro at the time... not exactly sure). After several months I began to experience narcoleptomimetic side effects though... too bad. I've heard Symmetrel (amantadine -- another dopamine agonist) may be a better option, though anyone I've spoken with whose tried Requip reports experiences identical to that which I went through with Mirapex.
Posted by linkadge on January 14, 2004, at 14:21:43
In reply to Re: Anyone tried mirapex ?, posted by Ame Sans Vie on January 14, 2004, at 13:12:57
When you discontinued it did you have withdrawl ?
Do you think that if you restarted it, you would have more effect ??
Also, what are you taking now ??
Linkadge
Posted by Ame Sans Vie on January 14, 2004, at 15:36:38
In reply to question for ame sans vie, posted by linkadge on January 14, 2004, at 14:21:43
There was absolutely no withdrawal, and from what I hear this is generally true with all dopamine agonists.
I think I achieved the maximum effect possible from the dose I was on (1.5mg three times daily -- the max FDA-approved dosage). I felt absolutely wonderful (and posted about Mirapex often here on PB) while I was taking it, until the sleep attacks kicked in.
Now I take 20mg Prozac, 60mg Adderall XR, and 8mg Klonopin for social anxiety, depression, generalized anxiety, agoraphobia, panic disorder, and a touch of OCD and ADD. I also switch back and forth every two weeks (to avoid tolerance) between one gram of chloral hydrate and 200mg of Tuinal for sleep.
Posted by kewlbleauwater on January 14, 2004, at 15:47:51
In reply to Anyone tried mirapex ?, posted by linkadge on January 14, 2004, at 10:41:43
I take 0.5mg to 1mg at night for restless legs
Posted by linkadge on January 14, 2004, at 16:06:29
In reply to Re: Anyone tried mirapex ?, posted by kewlbleauwater on January 14, 2004, at 15:47:51
do you think it affects your mood at all (ie in the morning ?))
Thanks -
Linkadge
Posted by kewlbleauwater on January 14, 2004, at 16:14:22
In reply to Re: Anyone tried mirapex ?, posted by linkadge on January 14, 2004, at 16:06:29
I am on imipramine and buspar for my depression and related anxiety. The mirapex came long before the aforementioned meds....and if I do not take it, I run in my sleep all night and do not get much rest, so my mood if affected by that. But, no, I do not notice any change in mood because of the chemical properties of Mirapex.
Posted by Maximus on January 16, 2004, at 14:42:40
In reply to Anyone tried mirapex ?, posted by linkadge on January 14, 2004, at 10:41:43
> Has anyone here tried mirapex ??
> With what other medications ?I don't take pramipexole myself. However pramipexole is more and more used in the treatment of bipolar depression with or without lamotrigine. It acts quickly (with a low risk of switching) and has a very safe profile. I have a relative of mine who has been on Mirapex for 1 year and he just swears by it.
Posted by jparsell82 on January 17, 2004, at 11:53:49
In reply to Re: Anyone tried mirapex ?, posted by SLS on January 14, 2004, at 11:41:38
> > Has anyone here tried mirapex ??
>
> Hi.
>
> I know of a few people who have tried it and eventually gave up on it. They reported a significant antidepressant effect early on. Then, for some reason, they began to feel sedated and became somnolent. I have very little idea how prevalent that pattern of response is.
>
> You might also take a look at ropinerole (Requip). My doctor mentioned it as a possible treatment for me.
>
>
> - ScottCould tyrosine supplementation possibly prevent this? I mean, does anyone have an idea why the effects change?
Posted by SLS on January 17, 2004, at 12:49:26
In reply to Re: Anyone tried mirapex ? » SLS, posted by jparsell82 on January 17, 2004, at 11:53:49
> > > Has anyone here tried mirapex ??
> > I know of a few people who have tried it and eventually gave up on it. They reported a significant antidepressant effect early on. Then, for some reason, they began to feel sedated and became somnolent. I have very little idea how prevalent that pattern of response is.
> Could tyrosine supplementation possibly prevent this? I mean, does anyone have an idea why the effects change?Off the top of my head, I wouldn't think that tyrosine of phenylalanine would help. It wouldn't hurt to try, though. I don't think the problem lies with dopamine depletion, but rather, changes in receptor sensitivity.
- Scott
Posted by jerrympls on January 17, 2004, at 23:24:36
In reply to Re: question for ame sans vie » linkadge, posted by Ame Sans Vie on January 14, 2004, at 15:36:38
> There was absolutely no withdrawal, and from what I hear this is generally true with all dopamine agonists.
>
> I think I achieved the maximum effect possible from the dose I was on (1.5mg three times daily -- the max FDA-approved dosage). I felt absolutely wonderful (and posted about Mirapex often here on PB) while I was taking it, until the sleep attacks kicked in.
>
> Now I take 20mg Prozac, 60mg Adderall XR, and 8mg Klonopin for social anxiety, depression, generalized anxiety, agoraphobia, panic disorder, and a touch of OCD and ADD. I also switch back and forth every two weeks (to avoid tolerance) between one gram of chloral hydrate and 200mg of Tuinal for sleep.Can you tell me more about the use of Mirapex and/or Amantadine for depression? Did you use them alone or as augmentors? What do you mean by sleep attacks? Is it common for someone to develop sleep attacks after being on Mirapex?
I'm a musician and have been without creativitiy and motivation to play, perform, compose for too long. I don't even listen to the wonderful symphonies I did before this darkness of depression hit 13 years ago. ANy info would be greatly appreciated - because I'd like to talk to my doc next week about it.
Much thanks!!!
Jerry
Posted by Festus on January 17, 2004, at 23:39:25
In reply to Re: question for ame sans vie » Ame Sans Vie, posted by jerrympls on January 17, 2004, at 23:24:36
I,too,would like some feedback on this situation:I am working with a 62 yr.old woman recovering from knee reconstructive surgery.The progress has been very slow and painful for her,cause she loves to exercise.It helps quell her RLS at night.She takes Mirapex for her RLS.Is this the main ailment the drug is Rx,ed for?What other things is it used for?My client is very depressed from not being able to exercise,but her Dr. gave her very restrictive rehab rules and she takes nothing else other than an occasional Celebrex.Festus
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