Psycho-Babble Medication Thread 262389

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Taking CYP2D6 inhibitor help with Adderall? (GBL)

Posted by btnd on September 22, 2003, at 11:06:49

I know that amphetamines are metabolized via CYP2D6 enzyme.
Would taking CYP2D6 inhibitor help with Adderall duration/effects?

Ame - I've read in your other posts that you have a supply of GBL. I also have, besides my RX for Xyrem - and just found that GBL is a CYP2D6 inhibitor.
I use Xyrem for night-time purposes and sometimes GBL during the day - because it's a great anti-anxiety treatment and relieves depression totally, unfortunately short-term.

Here is the study:

http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11813809&dopt=Abstract

Take care,
Brad

 

Re: Taking CYP2D6 inhibitor help with Adderall? (GBL) » btnd

Posted by Ame Sans Vie on September 23, 2003, at 8:31:03

In reply to Taking CYP2D6 inhibitor help with Adderall? (GBL), posted by btnd on September 22, 2003, at 11:06:49

Thanks for the abstract, I've been wondering which metabolic pathway GBL took. I don't usually use GBL itself though -- I usually react it with sodium hydroxide and ethanol to form GHB. Very simple process.


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