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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by jaby on May 25, 2002, at 16:49:33
I have GAD/depression/BP and am currently taking 2400mg Neurontin, 5 mg diazepam, 600 mg Lithobid, and 1.25 mg Zyprexa each day. The Lithobid and Zyprexa are new additions. I have taken lithium carbonate before, but with only minimal success. I am having many glimpses of feeling great! This is likely not a placebo effect (although I never throw any idea out alltogether), as I have really only responded to one other drug (lamictal-for a few months).
Okay, now my question...I usually feel really good in the morning, and then a little after noon I get very dizzy and my dizziness/dissociation, that was always my worst problem, appears in a mild form, but enough to prevent me from wanting to do things.
I would like to know what you guys think I can attribute this to? I realize my zyprexa dose is tiny and that could be the culprit (although it has quite a long half-life). I guess it could be just an adjustment thing too, as I have only been on these new meds about 5 days.
Let me know your thoughts. I know this may not last, but I have seen the beautiful world my friends! It is not a metaphor that things look brighter and the colors are more vibrant. It's real! Best of luck to all and I appreciate your comments.
Posted by Zo on May 26, 2002, at 3:21:43
In reply to Zyprexa Li working great, but I need your help.., posted by jaby on May 25, 2002, at 16:49:33
Jaby,Zyprexa really is a wonder drug--whatever you decide, I encourage you to adjust something else. It worked for me after fifteen years of trials. . I only gave it up because of big weight gain, which not everyone gets, and there are some suggestions now how to avoid it. . .WHOA! I just saw your Neurontin dose! I've taken Neurontin-- 2400mg would put me in a coma! IMO, you are *real* safe in reducing that! It's a very flexible drug, easy to decrease--and Zyprexa is sooo much more effective for BP, there's no comparison. It could be, too, that you simply *need* less Neurontin with both Zyprexa and Lithobid on board, so that your former dose is now too much.
Hope this helps--I know how you feel, my experience Zyprexa is a med you can trust. (If they're both new additons, though, why both? It's recommended to add one med at a time, in order to evaluate.
Zo
Posted by ChrisK on May 26, 2002, at 3:50:09
In reply to Zyprexa Li working great, but I need your help.., posted by jaby on May 25, 2002, at 16:49:33
You didn't say what time you take the Zyprexa. Since it is a once a day med I found that the best time for me was after dinner. The sedation (and sometimes dizziness) that it would cause would hit during the night and I woke up refreshed. Try adjusting what time you take it and your body will eventually adjust to it.
Posted by jaby on May 26, 2002, at 14:56:21
In reply to Re: Zyprexa Li working great, but I need your hel » jaby, posted by Zo on May 26, 2002, at 3:21:43
Hey guys,
Thanks for your response. 2400 mg Neurontin is actually less than I have taken in the past. I was up to 3600mg/day! It worked great for ruminations and a bit for the dissociation/dizziness.I stated both Lithobid and Zyprexa at the same because my sister had a severe (hospitalized, catatonic, ECT.) a few years ago. The ECT brought her back from the dead and now she takes Lithobid and Zyprexa and is better than she was before the whole episode took place. I would say that the anxiety/depression that I have experienced over the last 5 years is very similar to the way her ordeal started (hers advanced rather quickly though. Back to my point...my doctor and I decided to bag the idea of this being something different than what my sister had and she was dxed BP.
Again, I had taken regular lithium before without any terrific results.
I take only 1.25mg Zyprexa/day and dose it about 2 hours before i go to bed. I wake up feeling great, so I don't think it's the Zyprexa causing the dizziness. I kind of feel like the dizziness is an altered (improved form) of the dizziness/dissociation I have in the past. It is semi-crippling though. I am thinking of bumping the Zyprexa up to just 2.5mg (all at night) to see what happens. The dizziness starting after noon is weird though because zyprexa has such a long half-life. I am a very fast metabolizer though, so maybe I'm kicking it out pretty well. I'm not real concerned about the weight because I am fairly disciplined and work out like a maniac.
I think my sister was up to 10 mg Zyprexa at one time. She had trouble getting off about a decent time ago, but is now doing great (better than me) and only takes lithobid and neurontin.
Any ideas from you guys about the zyprexa dosing? Think I could be kicking out too quickly and that's the reason for the afternnon poop-out? I hope you guys are doing well. Thanks!
Posted by Zo on May 26, 2002, at 16:11:40
In reply to Re: Zyprexa Li working Zo Chris K., posted by jaby on May 26, 2002, at 14:56:21
I still maintain that adding another, powerful drug can alter the doses of drugs one is already taking.
Good Luck!
Zo
This is the end of the thread.
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