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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by rainbowlight on May 15, 2002, at 16:11:38
I am having a horrible melt down today, can't stop crying, getting very scared I might end up in the hospital. A month ago I added Zoloft to my meds, I felt great. After a month I felt like I had the flu, headache, backache. But it's not going away. My doctor thinks it is my Risperdal going too high, so she cut it in half. That was 3 days ago, now I can't stop crying and still feel physically ill. I feel like I am going downhill fast! I am wondering if I am having a med interaction? Or is one of my meds going too high?My meds are Lamictal, Remeron, Risperdal, Cogentin and Restoril, and the recently added Zoloft. I know you guys know alot more about meds and their interactions than I do, can someone help?
Posted by JohnX2 on May 15, 2002, at 19:00:14
In reply to Losing it fast, help please!, posted by rainbowlight on May 15, 2002, at 16:11:38
> I am having a horrible melt down today, can't stop crying, getting very scared I might end up in the hospital. A month ago I added Zoloft to my meds, I felt great. After a month I felt like I had the flu, headache, backache. But it's not going away. My doctor thinks it is my Risperdal going too high, so she cut it in half. That was 3 days ago, now I can't stop crying and still feel physically ill. I feel like I am going downhill fast! I am wondering if I am having a med interaction? Or is one of my meds going too high?My meds are Lamictal, Remeron, Risperdal, Cogentin and Restoril, and the recently added Zoloft. I know you guys know alot more about meds and their interactions than I do, can someone help?
Hi Rainbowlight,
I'm sorry you are going through such torture.
This past weekend my body became all achy, I was tired,
I had a cough, headache, stuffy nose...and I felt like had the flu.
I hadn't changed my medicines and the symptoms went away when
I took an antihistamine. I don't know if allergies flared up in
town or what? But now I feel better just a few days later.As far as the med interactions, I'm not too familiar
with Restoril and Cogentin.People have reported flu like symptoms when titrating Lamictal.
Maybe the Zoloft is somehow interacting? Is your body
temperature normal? I don't now. Sometimes when I add a new medicine I get a side effect flare up that is
more consistent with another medicine I was taking.Please hang in there. And don't be afraid to go to the
hospital if things are unbearable.Best Wishes,
John
Posted by Ritch on May 16, 2002, at 0:02:57
In reply to Losing it fast, help please!, posted by rainbowlight on May 15, 2002, at 16:11:38
> I am having a horrible melt down today, can't stop crying, getting very scared I might end up in the hospital. A month ago I added Zoloft to my meds, I felt great. After a month I felt like I had the flu, headache, backache. But it's not going away. My doctor thinks it is my Risperdal going too high, so she cut it in half. That was 3 days ago, now I can't stop crying and still feel physically ill. I feel like I am going downhill fast! I am wondering if I am having a med interaction? Or is one of my meds going too high?My meds are Lamictal, Remeron, Risperdal, Cogentin and Restoril, and the recently added Zoloft. I know you guys know alot more about meds and their interactions than I do, can someone help?
Rainbow,I just did some quick checking on your meds and it appears that the Risperdal, Zoloft, and Remeron (for sure) are *all* metabolized to varing extents by liver enzyme CYP2D6. What that means is that the blood levels of all of those respective medications are now possibly a dice-toss relative to what they were before you changed your med regimen by adding the Zoloft. I just think you are "too many changes to the wind" to figure out what is the culprit or what is causing problems. The only suggestion I've got given all of this is-call your pdoc yet again and explain this situation, possibly resume your med regimen immediately prior to the Zoloft add and let your blood levels stabilize-then *get* blood levels of all of your meds and then make the change and remonitor. I couldn't find anything that helpful for Lamictal blood levels and other meds affecting it except that Depakote will boost it (not much help). I think your pdoc is probably on the right "track" in the sense that a med is causing another to accumulate excessively or clear too quickly, i.e. The trouble of course is *which* one? If you feel like you need to go to the ER, then just go and explain all of this to the ER doc and let them handle it.
good grief, I hope this gets straightened out
soon,Mitch
Posted by rainbowlight on May 16, 2002, at 1:08:07
In reply to Re: Losing it fast, help please! » rainbowlight, posted by Ritch on May 16, 2002, at 0:02:57
she thinks it is the Zoloft now! I would tend to agree since these problems came up a month after I started the Zoloft. She wants me to cut it from 37.5 mgs. to 12 mgs. I am praying this works. She also told me not to discontinue the Risperdal right now, it is making my moods swing all over the place. Spent the better part of my night bawling my eyes out, not fun! It is so frustrating to have problems with the Zoloft, it is the first med that made me feel so much better. I hope tomorrow is better, I'll let you know how I'm doing. Pray it works for me! Thanks again, you guys are great.
Posted by Ritch on May 16, 2002, at 9:18:11
In reply to Thanks for the support, I spoke to pdoc and.., posted by rainbowlight on May 16, 2002, at 1:08:07
Posted by katekite on May 16, 2002, at 12:12:10
In reply to Thanks for the support, I spoke to pdoc and.., posted by rainbowlight on May 16, 2002, at 1:08:07
Posted by BarbaraCat on May 17, 2002, at 16:34:10
In reply to Thanks for the support, I spoke to pdoc and.., posted by rainbowlight on May 16, 2002, at 1:08:07
Sure is scary when those meltdowns occur. We think were getting maimed forever, but somehow we always pull through. I had a panic reaction to too much Zoloft that went on for a year - was up to almost 300 mg at the peak cause it wasn't helping the depression any more so doctor kept bumping it up.
I'll keep you on my prayer list. Not sure exactly who it is I'm praying to, but there's got to be some Greater Power somewhere that loves us. I've been supplicating it a whole lot lately. - BCat
> she thinks it is the Zoloft now! I would tend to agree since these problems came up a month after I started the Zoloft. She wants me to cut it from 37.5 mgs. to 12 mgs. I am praying this works. She also told me not to discontinue the Risperdal right now, it is making my moods swing all over the place. Spent the better part of my night bawling my eyes out, not fun! It is so frustrating to have problems with the Zoloft, it is the first med that made me feel so much better. I hope tomorrow is better, I'll let you know how I'm doing. Pray it works for me! Thanks again, you guys are great.
Posted by deli on May 17, 2002, at 20:33:25
In reply to Losing it fast, help please!, posted by rainbowlight on May 15, 2002, at 16:11:38
This is the end of the thread.
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