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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by laurai on August 9, 2001, at 9:23:04
I was taking Inderal for anxiety, but it caused a
severe depression. So I stopped cold-turkey. I was only taking 20mg a day.Has anyone ever heard of Inderal (Propranolol) withdrawal? Does it cause insomnia?
I haven't slept in 3 days. But I don't want to go back on the Inderal - the depression was horrible.
I'm also taking Neurontin and Elavil. I don't think there should be any kind of interaction.
Posted by SalArmy4me on August 9, 2001, at 10:46:00
In reply to inderal side effects and withdrawal, posted by laurai on August 9, 2001, at 9:23:04
Kirk, Julienne K. PharmD. Johnson, Scott H. MD. Safe Discontinuation of Antihypertensive Therapy. Archives of Family Medicine. 4(3):266-270, March 1995:
"Manifestations of Antidepressant Withdrawal Syndrome (AWS) often resemble those encountered in patients with sympathetic hyperactivity. Subjective symptoms usually begin during the first 12 to 72 hours after cessation of treatment [4,5]. Commonly experienced central nervous system effects include nervousness, agitation, insomnia, anxiety, and headaches [1,6,7]. Gastrointestinal effects range from mild nausea to anorexia, abdominal cramps, and vomiting. Other symptoms are sweating, palpitations, tremor, and fatigue. The observable signs of withdrawal frequently include tachycardia, increased blood pressure, and diaphoresis. In some cases, elevations have been noted in urinary catecholamine concentrations [8]. Withdrawal symptoms have been reported to persist for periods varying from 2 to 7 days [1,6,7]. While these symptoms resolve spontaneously with time, restarting the original antihypertensive therapy relieves both signs and symptoms rapidly...
To discontinue beta-blocker therapy, the dose should be reduced over a 7- to 10-day period to a dose equivalent to 30 mg/d of propranolol hydrochloride and then maintained at the same dose for 2 weeks to prevent AWS..."
Posted by irishcatholic on August 9, 2001, at 12:52:12
In reply to Re: inderal side effects and withdrawal » laurai, posted by SalArmy4me on August 9, 2001, at 10:46:00
I can personally attest to beta-blocker induced depression.
My internist disagrees but I have found plenty of
evidence backing up the depressive effects. However, like so many meds, stopping suddenly is not a good idea.
Hopefully your A/D will overcome it once you taper off.
Good luck!
Posted by MB on August 9, 2001, at 13:00:32
In reply to inderal side effects and withdrawal, posted by laurai on August 9, 2001, at 9:23:04
Inderal is THE DEVIL
...oh, wait, did i say that outloud...?
This is the end of the thread.
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