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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by ryan_s on February 19, 2000, at 2:54:44
i have tried many antidepressants. people in this discussion group suggest that i try nortip. i have a few questions before i ask my pdoc to perscribe this tca. from personal experience is there a huge difference between ssri's and nortip? does nortip cause emotional numbing like the ssri's? does nortip in general give patients a sense of well being?
thank you for your time!ryan_s
Posted by JohnL on February 19, 2000, at 4:33:01
In reply to those experienced with nortip (pamelor) apply here, posted by ryan_s on February 19, 2000, at 2:54:44
> i have tried many antidepressants. people in this discussion group suggest that i try nortip. i have a few questions before i ask my pdoc to perscribe this tca. from personal experience is there a huge difference between ssri's and nortip? does nortip cause emotional numbing like the ssri's? does nortip in general give patients a sense of well being?
> thank you for your time!
>
> ryan_sRyan,
Only a personal trial will tell. We're all so different in metabolism, genetics, and underlying chemical imbalance. I wish there was an easier way to predict. But in general, if you have already been disappointed with serotonin antidepressants, it might make sense to briefly explore an NE antidepressant like Nortrip. And if no better results, move on to completely different class of drugs outside of the antidepressant bandwagon. No sense in trying zillions of antidepressants when the particular individual's chemical imblance is something an antidepressant won't fix.
Posted by ChrisK on February 19, 2000, at 7:17:03
In reply to Re: those experienced with nortip (pamelor) apply here, posted by JohnL on February 19, 2000, at 4:33:01
I am currently taking 100 mg of Nortrip per day. I didn't react to SSRI's at all. My father was depressive and did well on amitriptyline so I asked my pdoc if we could give the TCA's a try. Due to some liver problems and a history of suicide problems he put me on Nortrip instead of one of the other TCA's.
It defiinitely made an improvement over anything I had tried before. The only other one in the past I reacted to was Immiprimine. The only problem was that it didn't bring me all the way back to something close to normal. I still had suicidal ideations so he gave me a medium dose of Zyprexa that got me over that hump.
Now I have a cocktail that includes Nortrip, Zyprexa, Naltrexone and Wellbutrin. It's working so far. I have had the most normal feeling this winter than I've had in 20 years. I would definitely give the Nortrip a chance as you haven't responded to the SSRI's.
Good Luck with it,
Chris
Posted by Cam W. on February 19, 2000, at 11:21:37
In reply to Re: those experienced with nortip (pamelor) apply here, posted by ChrisK on February 19, 2000, at 7:17:03
> I am currently taking 100 mg of Nortrip per day. I didn't react to SSRI's at all. My father was depressive and did well on amitriptyline so I asked my pdoc if we could give the TCA's a try. Due to some liver problems and a history of suicide problems he put me on Nortrip instead of one of the other TCA's.
>
> It defiinitely made an improvement over anything I had tried before. The only other one in the past I reacted to was Immiprimine. The only problem was that it didn't bring me all the way back to something close to normal. I still had suicidal ideations so he gave me a medium dose of Zyprexa that got me over that hump.
>
> Now I have a cocktail that includes Nortrip, Zyprexa, Naltrexone and Wellbutrin. It's working so far. I have had the most normal feeling this winter than I've had in 20 years. I would definitely give the Nortrip a chance as you haven't responded to the SSRI's.
>
> Good Luck with it,
> Chrisryan - I have noticed that nortriptyline works well in most people for the treatment of acute major depression, but once the depression resolves, 'some' people stop responding to it. There have been many articles written that include this observations, as well. The possible reasons for this are weak (non-compliance, change in disease state, etc.), but it is an interesting phenomenon. Does nortriptyline work as a maintenance antidepressant over the long-term? In some people, yes; in other people, no. I don't have any easy answer to this. Sincerely - Cam W.
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